Recent Publications

Highlight

writing

Authored by SEATRAC Leadership and members

This is unpublished

Jan-Mar 2024

 

Exposure to Mycobacterium remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection.

Mai D, Jahn A, Murray T, Morikubo M, Lim PN, Cervantes MM, Pham LK, Nemeth J, Urdahl K, Diercks AH, Aderem A, Rothchild AC.

PLoS Pathog. 2024 Jan 18;20(1):e1011871. doi: 10.1371/journal.ppat.1011871. eCollection 2024 Jan.

PMID: 38236787 Free PMC article.
Oral swabs with a rapid molecular diagnostic test for pulmonary tuberculosis in adults and children: a systematic review.

Church EC, Steingart KR, Cangelosi GA, Ruhwald M, Kohli M, Shapiro AE.

Lancet Glob Health. 2024 Jan;12(1):e45-e54. doi: 10.1016/S2214-109X(23)00469-2.

PMID: 38097297 Free PMC article.
Mycobacterium tuberculosis-dependent monocyte expression quantitative trait loci, cytokine production, and TB pathogenesis.

Hong H, Dill-McFarland KA, Simmons JD, Peterson GJ, Benchek P, Mayanja-Kizza H, Boom WH, Stein CM, Hawn TR.

Front Immunol. 2024 Mar 7;15:1359178. doi: 10.3389/fimmu.2024.1359178. eCollection 2024.

PMID: 38515745 Free PMC article.
MSMEG_0918 is not Essential for the Growth of Mycobacteriumsmegmatis.

Bedru E, Bhagwat A, Parish T.

MicroPubl Biol. 2024 Feb 6;2024:10.17912/micropub.biology.000891. doi: 10.17912/micropub.biology.000891. eCollection 2024.

PMID: 38404920 Free PMC article.
Regulatory Intersection of Two-component System and Ser/Thr Protein Kinase Signaling in Mycobacterium tuberculosis.

Frando A, Boradia V, Grundner C.

J Mol Biol. 2024 Jan 15;436(2):168379. doi: 10.1016/j.jmb.2023.168379. Epub 2023 Dec 1.

PMID: 38043732
Tuberculosis Infectiousness is Associated with Distinct Clinical and Inflammatory Profiles.

Horne D, Nduba V, Njagi L, Murithi W, Mwongera Z, Logioia G, Peterson G, Segnitz RM, Fennelly K, Hawn T.

Res Sq [Preprint]. 2024 Jan 10:rs.3.rs-3722244. doi: 10.21203/rs.3.rs-3722244/v1.

PMID: 38328225 Free PMC article. Preprint.
TBscreen: A passive cough classifier for tuberculosis screening with a controlled dataset.

Sharma M, Nduba V, Njagi LN, Murithi W, Mwongera Z, Hawn TR, Patel SN, Horne DJ.

Sci Adv. 2024 Jan 5;10(1):eadi0282. doi: 10.1126/sciadv.adi0282. Epub 2024 Jan 3.

PMID: 38170773 Free PMC article.
Towards pharmacogenomics-guided tuberculosis (TB) therapy: N-acetyltransferase-2 genotypes among TB-infected Kenyans of mixed ethnicity.

Njagi LN, Mecha JO, Mureithi MW, Otieno LE, Nduba V.

BMC Med Genomics. 2024 Jan 6;17(1):14. doi: 10.1186/s12920-023-01788-1.

PMID: 38184575 Free PMC article.
TOLLIP inhibits lipid accumulation and the integrated stress response in alveolar macrophages to control Mycobacterium tuberculosis infection.

Venkatasubramanian S, Plumlee CR, Dill-McFarland KA, Cohen SB, Gern BH, Rane DA, Meyer MK, Saha A, Hinderstein SA, Pearson GL, Lietzke AC, Pacheco A, Chow YH, Hung CF, Soleimanpour SA, Altman M, Urdahl KB, Shah JA.

Nat Microbiol. 2024 Apr;9(4):949-963. doi: 10.1038/s41564-024-01641-w. Epub 2024 Mar 25.

PMID: 38528148
Biomarker-confirmed suboptimal adherence to isoniazid preventive therapy among children with HIV in western Kenya.

Onyango DO, van der Sande MAB, Yuen CM, Were J, Mecha J, Njagi LN, Panpradist N, Matemo D, Leon D, Lutz B, Kinuthia J, John-Stewart G, Lacourse SM.

AIDS. 2024 Jan 1;38(1):39-47. doi: 10.1097/QAD.0000000000003719. Epub 2023 Sep 28.

PMID: 37773037
Usability testing of a mobile health application to support individuals with active tuberculosis: a mixed methods study.

Stabile AJ, Iribarren S, Sonney J, Demiris G, Schnall R.

Inform Health Soc Care. 2024 Mar 26:1-13. doi: 10.1080/17538157.2024.2333379. Online ahead of print.

PMID: 38529729
Effect of tuberculosis-HIV co-treatment on clinical and growth outcomes among hospitalized children newly initiating antiretroviral therapy.

Cherkos AS, Cranmer LM, Njuguna I, LaCourse SM, Mugo C, Moraa H, Maleche-Obimbo E, Enquobahrie DA, Richardson BA, Wamalwa D, John-Stewart G.

AIDS. 2024 Mar 15;38(4):579-588. doi: 10.1097/QAD.0000000000003797. Epub 2023 Nov 27.

PMID: 38016160
Maternal HIV Status and Risk of Infant Mycobacterium tuberculosis Infection as Measured by Tuberculin Skin Test.

Mecha J, Escudero JN, Richardson BA, Maleche-Obimbo E, Matemo D, Kinuthia J, John-Stewart G, LaCourse SM.

Pediatr Infect Dis J. 2024 Mar 1;43(3):250-256. doi: 10.1097/INF.0000000000004190. Epub 2023 Nov 22.

PMID: 37991383
Molecular detection of pre-ribosomal RNAs of Mycobacterium bovis bacille Calmette-Guérin and Mycobacterium tuberculosis to enhance pre-clinical tuberculosis drug and vaccine development.

Chang M, Venkatasubramanian S, Barrett H, Urdahl KB, Weigel KM, Cangelosi GA, Shah JA, Saha A, Feng L, Adams KN, Sherman DR, Smith N, Seshadri C, Kublin JG, Murphy SC.

Diagn Microbiol Infect Dis. 2024 Jan;108(1):116106. doi: 10.1016/j.diagmicrobio.2023.116106. Epub 2023 Oct 16.

PMID: 37931386 Free PMC article.
Epigenetic programming of host lipid metabolism associates with resistance to TST/IGRA conversion after exposure to Mycobacterium tuberculosis.

Dill-McFarland KA, Simmons JD, Peterson GJ, Nguyen FK, Campo M, Benchek P, Stein CM, Vaisar T, Mayanja-Kizza H, Boom WH, Hawn TR.

bioRxiv [Preprint]. 2024 Mar 4:2024.02.27.582348. doi: 10.1101/2024.02.27.582348.

PMID: 38464296 Free PMC article. Preprint.
Interpreter usage and associations with latent tuberculosis infection treatment acceptance and completion in the USA among non-U.S.-born persons, 2012-2017.

Gonzalez-Reyes R, Katz D, Lambert L, Sorri Y, Narita M, Horne DJ; Tuberculosis Epidemiologic Studies Consortium.

PLoS One. 2024 Apr 16;19(4):e0298628. doi: 10.1371/journal.pone.0298628. eCollection 2024.

PMID: 38625902 Free PMC article.
Maternal breastfeeding and education impact infant growth and development more than in-utero HIV/antiretroviral therapy exposure in context of universal antiretroviral therapy.

Cherkos AS, LaCourse SM, Kinuthia J, Mecha J, Enquobahrie DA, Escudero JN, John-Stewart G.

AIDS. 2024 Mar 15;38(4):537-546. doi: 10.1097/QAD.0000000000003785. Epub 2023 Nov 14.

PMID: 37967230
Diagnostic accuracy of tongue swab testing on two automated tuberculosis diagnostic platforms, Cepheid Xpert MTB/RIF Ultra and Molbio Truenat MTB Ultima.

Wood RC, Luabeya AK, Dragovich RB, Olson AM, Lochner KA, Weigel KM, Codsi R, Mulenga H, de Vos M, Kohli M, Penn-Nicholson A, Hatherill M, Cangelosi GA.

J Clin Microbiol. 2024 Apr 10;62(4):e0001924. doi: 10.1128/jcm.00019-24. Epub 2024 Mar 14.

PMID: 38483169 Free PMC article.