July-September 2024
Probing Dermal Immunity to Mycobacteria through a Controlled Human Infection Model.
Church EC, Bishop E, Fiore-Gartland A, Yu KKQ, Chang M, Jones RM, Brache JK, Ballweber Fleming L, Phan JM, Makatsa MS, Heptinstall J, Chiong K, Dintwe O, Naidoo A, Voillet V, Mayer-Blackwell K, Nwanne G, Andersen-Nissen E, Vary JC Jr, Tomaras GD, McElrath MJ, Sherman DR, Murphy SC, Kublin JG, Seshadri C.Immunohorizons. 2024 Sep 1;8(9):695-711. doi: 10.4049/immunohorizons.2400053.PMID: 39283647 Clinical Trial.
Nduba V, Njagi LN, Murithi W, Mwongera Z, Byers J, Logioia G, Peterson G, Segnitz RM, Fennelly K, Hawn TR, Horne DJ.Nat Commun. 2024 Sep 1;15(1):7604. doi: 10.1038/s41467-024-52122-x.PMID: 39217183
Developing an AI-Assisted Platform to Support Tuberculosis Care Delivery.
Iribarren S, Yuwen W, de Cock M.Stud Health Technol Inform. 2024 Aug 22;316:839-840. doi: 10.3233/SHTI240542.PMID: 39176923
Suyanto A, Iribarren S, Turner AM.Stud Health Technol Inform. 2024 Aug 22;316:228-229. doi: 10.3233/SHTI240386.PMID: 39176715
Dill-McFarland KA, Simmons JD, Peterson GJ, Nguyen FK, Campo M, Benchek P, Stein CM, Vaisar T, Mayanja-Kizza H, Boom WH, Hawn TR.mSystems. 2024 Sep 17;9(9):e0062824. doi: 10.1128/msystems.00628-24. Epub 2024 Aug 20.PMID: 39162406
Cherkos AS, LaCourse SM, Enquobahrie DA, Escudero JN, Mecha J, Matemo D, Kinuthia J, Iribarren SJ, John-Stewart G.PLoS One. 2024 Aug 16;19(8):e0293708. doi: 10.1371/journal.pone.0293708. eCollection 2024.PMID: 39150949 Clinical Trial.
Iribarren S, Vidrio AA.Stud Health Technol Inform. 2024 Jul 24;315:180-184. doi: 10.3233/SHTI240130.PMID: 39049249
Cirillo D, Anthony R, Gagneux S, Horsburgh CR Jr, Hasan R, Darboe S, Laniado-Laborin R, Probandari A, Tukvadze N, Arcêncio RA, Bimba JS, Brighenti S, Chesov D, Chiang CY, Kalmambetova G, Knight G, Konstantynovska O, Kruse A, Lange C, Mayanja-Kizza H, McBryde E, Min J, Sanchez-Montalva A, Sulis G, Tsogt B, Van Der Walt M, Yeboah-Manu D, Hauser J.Lancet Glob Health. 2024 Aug;12(8):e1225-e1226. doi: 10.1016/S2214-109X(24)00229-8.PMID: 39030054
Chabala C, Roucher C, Ton Nu Nguyet MH, Babirekere E, Inambao M, Businge G, Kapula C, Shankalala P, Nduna B, Mulenga V, Graham S, Wobudeya E, Bonnet M, Marcy O; TB-Speed SAM study group.EClinicalMedicine. 2024 Jun 20;73:102688. doi: 10.1016/j.eclinm.2024.102688. eCollection 2024 Jul.PMID: 39007063
Sun M, Phan JM, Kieswetter NS, Huang H, Yu KKQ, Smith MT, Liu YE, Wang C, Gupta S, Obermoser G, Maecker HT, Krishnan A, Suresh S, Gupta N, Rieck M, Acs P, Ghanizada M, Chiou SH, Khatri P, Boom WH, Hawn TR, Stein CM, Mayanja-Kizza H, Davis MM, Seshadri C.Nat Immunol. 2024 Aug;25(8):1411-1421. doi: 10.1038/s41590-024-01897-8. Epub 2024 Jul 12.PMID: 38997431
Bijker EM, Horn L, LaCourse S, MacLean EL, Marais BJ, Nicol MP, Olbrich L, Seddon JA, Sutherland JS, Song R, Zar HJ, Jaganath D; Child TB Diagnostics Consensus Group.Lancet Infect Dis. 2024 Jul 3:S1473-3099(24)00339-6. doi: 10.1016/S1473-3099(24)00339-6. Online ahead of print.PMID: 38971177 Review.
Njagi LN, Kaguthi G, Mecha JO, Hawn TR, Nduba V.Tuberculosis (Edinb). 2024 Jul;147:102514. doi: 10.1016/j.tube.2024.102514. Epub 2024 May 5.PMID: 38723342
April-June 2024
Mapping TB incidence across districts in Uganda to inform health program activities.
Henry NJ, Zawedde-Muyanja S, Majwala RK, Turyahabwe S, Barnabas RV, Reiner RC Jr, Moore CE, Ross JM.IJTLD Open. 2024 May 1;1(5):223-229. doi: 10.5588/ijtldopen.23.0624. eCollection 2024 May.PMID: 39022779 Free PMC article.
Host and pathogen genetic diversity shape vaccine-mediated protection to Mycobacterium tuberculosis.
Cohen SB, Plumlee CR, Engels L, Mai D, Murray TA, Jahn AN, Alexander B, Delahaye JL, Cross LM, Maciag K, Schrader S, Durga K, Gold ES, Aderem A, Gerner MY, Gern BH, Diercks AH, Urdahl KB. Front Immunol. 2024 Jun 28;15:1427846. doi: 10.3389/fimmu.2024.1427846. eCollection 2024.PMID: 39007152 Free PMC article.
Williams BD, Ferede D, Abdelaal HFM, Berube BJ, Podell BK, Larsen SE, Baldwin SL, Coler RN. Front Immunol. 2024 Jun 20;15:1424374. doi: 10.3389/fimmu.2024.1424374. eCollection 2024.PMID: 38966641 Free PMC article.
Airway microbiome signature accurately discriminates Mycobacterium tuberculosis infection status.
Kayongo A, Ntayi ML, Olweny G, Kyalo E, Ndawula J, Ssengooba W, Kigozi E, Kalyesubula R, Munana R, Namaganda J, Caroline M, Sekibira R, Bagaya BS, Kateete DP, Joloba ML, Jjingo D, Sande OJ, Mayanja-Kizza H. iScience. 2024 May 28;27(6):110142. doi: 10.1016/j.isci.2024.110142. eCollection 2024 Jun 21.PMID: 38904070 Free PMC article.
Dintwe OB, Ballweber Fleming L, Voillet V, McNevin J, Seese A, Naidoo A, Omarjee S, Bekker LG, Kublin JG, De Rosa SC, Newell EW, Fiore-Gartland A, Andersen-Nissen E, McElrath MJ.Nat Commun. 2024 Jun 18;15(1):5191. doi: 10.1038/s41467-024-49050-1.PMID: 38890283 Free PMC article. Clinical Trial.
Njagi LN, Kaguthi G, Mecha JO, Hawn TR, Nduba V. Tuberculosis (Edinb). 2024 Jul;147:102514. doi: 10.1016/j.tube.2024.102514. Epub 2024 May 5.PMID: 38723342 Free PMC article.
Cross DL, Layton ED, Yu KK, Smith MT, Aguilar MS, Li S, Wilcox EC, Chapuis AG, Mayanja-Kizza H, Stein CM, Boom WH, Hawn TR, Bradley P, Newell EW, Seshadri C. JCI Insight. 2024 May 8;9(9):e166505. doi:10.1172/jci.insight.166505.PMID: 38716731 Free PMC article.
Gutierrez J, Nsereko M, Malone LL, Mayanja-Kizza H, Kisingo H, Boom WH, Bark CM, Stein CM. Trop Med Infect Dis. 2024 Apr 11;9(4):81. doi: 10.3390/tropicalmed9040081.PMID: 38668542 Free PMC article.
Age and sex influence antibody profiles associated with tuberculosis progression.
Davies LRL, Wang C, Steigler P, Bowman KA, Fischinger S, Hatherill M, Fisher M, Mbandi SK, Rodo M, Ottenhoff THM, Dockrell HM, Sutherland JS, Mayanja-Kizza H, Boom WH, Walzl G, Kaufmann SHE, Nemes E, Scriba TJ, Lauffenburger D, Alter G, Fortune SM. Nat Microbiol. 2024 Jun;9(6):1513-1525. doi: 10.1038/s41564-024-01678-x. Epub 2024 Apr 24.PMID: 38658786 Free PMC article.
Gonzalez-Reyes R, Katz D, Lambert L, Sorri Y, Narita M, Horne DJ; Tuberculosis Epidemiologic Studies Consortium.PLoS One. 2024 Apr 16;19(4):e0298628. doi: 10.1371/journal.pone.0298628. eCollection 2024.PMID: 38625902 Free PMC article.
Maciag K, Plumlee C, Cohen S, Gern B, Urdahl K. bioRxiv [Preprint]. 2024 Apr 5:2024.04.04.588086. doi: 10.1101/2024.04.04.588086.Update in: J Immunol. 2024 Aug 1;213(3):339-346. doi: 10.4049/jimmunol.2400145.PMID: 38617280 Free PMC article. Preprint.
Ayers T, Hill AN, Raykin J, Mohanty S, Belknap RW, Brostrom R, Khurana R, Lauzardo M, Miller TL, Narita M, Pettit AC, Pyan A, Salcedo KL, Polony A, Flood J; CDC Tuberculosis Epidemiologic Studies Consortium. JAMA Netw Open. 2024 Apr 1;7(4):e244769. doi: 10.1001/jamanetworkopen.2024.4769.PMID: 38568690 Free PMC article.
Stabile AJ, Iribarren S, Sonney J, Demiris G, Schnall R. Inform Health Soc Care. 2024 Apr 2;49(2):136-148. doi: 10.1080/17538157.2024.2333379. Epub 2024 Mar 26.PMID: 38529729
Jan-Mar 2024
| Exposure to Mycobacterium remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection.
Mai D, Jahn A, Murray T, Morikubo M, Lim PN, Cervantes MM, Pham LK, Nemeth J, Urdahl K, Diercks AH, Aderem A, Rothchild AC. PLoS Pathog. 2024 Jan 18;20(1):e1011871. doi: 10.1371/journal.ppat.1011871. eCollection 2024 Jan. PMID: 38236787 Free PMC article. |
| Oral swabs with a rapid molecular diagnostic test for pulmonary tuberculosis in adults and children: a systematic review.
Church EC, Steingart KR, Cangelosi GA, Ruhwald M, Kohli M, Shapiro AE. Lancet Glob Health. 2024 Jan;12(1):e45-e54. doi: 10.1016/S2214-109X(23)00469-2. PMID: 38097297 Free PMC article. |
| Mycobacterium tuberculosis-dependent monocyte expression quantitative trait loci, cytokine production, and TB pathogenesis.
Hong H, Dill-McFarland KA, Simmons JD, Peterson GJ, Benchek P, Mayanja-Kizza H, Boom WH, Stein CM, Hawn TR. Front Immunol. 2024 Mar 7;15:1359178. doi: 10.3389/fimmu.2024.1359178. eCollection 2024. PMID: 38515745 Free PMC article. |
| MSMEG_0918 is not Essential for the Growth of Mycobacteriumsmegmatis.
Bedru E, Bhagwat A, Parish T. MicroPubl Biol. 2024 Feb 6;2024:10.17912/micropub.biology.000891. doi: 10.17912/micropub.biology.000891. eCollection 2024. PMID: 38404920 Free PMC article. |
| Regulatory Intersection of Two-component System and Ser/Thr Protein Kinase Signaling in Mycobacterium tuberculosis.
Frando A, Boradia V, Grundner C. J Mol Biol. 2024 Jan 15;436(2):168379. doi: 10.1016/j.jmb.2023.168379. Epub 2023 Dec 1. PMID: 38043732 |
| Tuberculosis Infectiousness is Associated with Distinct Clinical and Inflammatory Profiles.
Horne D, Nduba V, Njagi L, Murithi W, Mwongera Z, Logioia G, Peterson G, Segnitz RM, Fennelly K, Hawn T. Res Sq [Preprint]. 2024 Jan 10:rs.3.rs-3722244. doi: 10.21203/rs.3.rs-3722244/v1. PMID: 38328225 Free PMC article. Preprint. |
| TBscreen: A passive cough classifier for tuberculosis screening with a controlled dataset.
Sharma M, Nduba V, Njagi LN, Murithi W, Mwongera Z, Hawn TR, Patel SN, Horne DJ. Sci Adv. 2024 Jan 5;10(1):eadi0282. doi: 10.1126/sciadv.adi0282. Epub 2024 Jan 3. PMID: 38170773 Free PMC article. |
| Towards pharmacogenomics-guided tuberculosis (TB) therapy: N-acetyltransferase-2 genotypes among TB-infected Kenyans of mixed ethnicity.
Njagi LN, Mecha JO, Mureithi MW, Otieno LE, Nduba V. BMC Med Genomics. 2024 Jan 6;17(1):14. doi: 10.1186/s12920-023-01788-1. PMID: 38184575 Free PMC article. |
| TOLLIP inhibits lipid accumulation and the integrated stress response in alveolar macrophages to control Mycobacterium tuberculosis infection.
Venkatasubramanian S, Plumlee CR, Dill-McFarland KA, Cohen SB, Gern BH, Rane DA, Meyer MK, Saha A, Hinderstein SA, Pearson GL, Lietzke AC, Pacheco A, Chow YH, Hung CF, Soleimanpour SA, Altman M, Urdahl KB, Shah JA. Nat Microbiol. 2024 Apr;9(4):949-963. doi: 10.1038/s41564-024-01641-w. Epub 2024 Mar 25. PMID: 38528148 |
| Biomarker-confirmed suboptimal adherence to isoniazid preventive therapy among children with HIV in western Kenya.
Onyango DO, van der Sande MAB, Yuen CM, Were J, Mecha J, Njagi LN, Panpradist N, Matemo D, Leon D, Lutz B, Kinuthia J, John-Stewart G, Lacourse SM. AIDS. 2024 Jan 1;38(1):39-47. doi: 10.1097/QAD.0000000000003719. Epub 2023 Sep 28. PMID: 37773037 |
| Usability testing of a mobile health application to support individuals with active tuberculosis: a mixed methods study.
Stabile AJ, Iribarren S, Sonney J, Demiris G, Schnall R. Inform Health Soc Care. 2024 Mar 26:1-13. doi: 10.1080/17538157.2024.2333379. Online ahead of print. PMID: 38529729 |
| Effect of tuberculosis-HIV co-treatment on clinical and growth outcomes among hospitalized children newly initiating antiretroviral therapy.
Cherkos AS, Cranmer LM, Njuguna I, LaCourse SM, Mugo C, Moraa H, Maleche-Obimbo E, Enquobahrie DA, Richardson BA, Wamalwa D, John-Stewart G. AIDS. 2024 Mar 15;38(4):579-588. doi: 10.1097/QAD.0000000000003797. Epub 2023 Nov 27. PMID: 38016160 |
| Maternal HIV Status and Risk of Infant Mycobacterium tuberculosis Infection as Measured by Tuberculin Skin Test.
Mecha J, Escudero JN, Richardson BA, Maleche-Obimbo E, Matemo D, Kinuthia J, John-Stewart G, LaCourse SM. Pediatr Infect Dis J. 2024 Mar 1;43(3):250-256. doi: 10.1097/INF.0000000000004190. Epub 2023 Nov 22. PMID: 37991383 |
| Molecular detection of pre-ribosomal RNAs of Mycobacterium bovis bacille Calmette-Guérin and Mycobacterium tuberculosis to enhance pre-clinical tuberculosis drug and vaccine development.
Chang M, Venkatasubramanian S, Barrett H, Urdahl KB, Weigel KM, Cangelosi GA, Shah JA, Saha A, Feng L, Adams KN, Sherman DR, Smith N, Seshadri C, Kublin JG, Murphy SC. Diagn Microbiol Infect Dis. 2024 Jan;108(1):116106. doi: 10.1016/j.diagmicrobio.2023.116106. Epub 2023 Oct 16. PMID: 37931386 Free PMC article. |
| Epigenetic programming of host lipid metabolism associates with resistance to TST/IGRA conversion after exposure to Mycobacterium tuberculosis.
Dill-McFarland KA, Simmons JD, Peterson GJ, Nguyen FK, Campo M, Benchek P, Stein CM, Vaisar T, Mayanja-Kizza H, Boom WH, Hawn TR. bioRxiv [Preprint]. 2024 Mar 4:2024.02.27.582348. doi: 10.1101/2024.02.27.582348. PMID: 38464296 Free PMC article. Preprint. |
| Interpreter usage and associations with latent tuberculosis infection treatment acceptance and completion in the USA among non-U.S.-born persons, 2012-2017.
Gonzalez-Reyes R, Katz D, Lambert L, Sorri Y, Narita M, Horne DJ; Tuberculosis Epidemiologic Studies Consortium. PLoS One. 2024 Apr 16;19(4):e0298628. doi: 10.1371/journal.pone.0298628. eCollection 2024. PMID: 38625902 Free PMC article. |
| Maternal breastfeeding and education impact infant growth and development more than in-utero HIV/antiretroviral therapy exposure in context of universal antiretroviral therapy.
Cherkos AS, LaCourse SM, Kinuthia J, Mecha J, Enquobahrie DA, Escudero JN, John-Stewart G. AIDS. 2024 Mar 15;38(4):537-546. doi: 10.1097/QAD.0000000000003785. Epub 2023 Nov 14. PMID: 37967230 |
| Diagnostic accuracy of tongue swab testing on two automated tuberculosis diagnostic platforms, Cepheid Xpert MTB/RIF Ultra and Molbio Truenat MTB Ultima.
Wood RC, Luabeya AK, Dragovich RB, Olson AM, Lochner KA, Weigel KM, Codsi R, Mulenga H, de Vos M, Kohli M, Penn-Nicholson A, Hatherill M, Cangelosi GA. J Clin Microbiol. 2024 Apr 10;62(4):e0001924. doi: 10.1128/jcm.00019-24. Epub 2024 Mar 14. PMID: 38483169 Free PMC article. |