presented by
TRTC
UW Tuberculosis Research and Training Center
SEATRAC
Fred Hutch, University of Washington, Seattle Children's
Sponsored in part by
Seattle Children's
Research Institute
Overview
Focusing on basic science, the 2024 Pacific Tuberculosis Pathogenesis and Host-Response Research Retreat (PacTB) will feature early-stage investigator talks and posters.
May 6th, 1:00pm - 6:00pm, PT
May 7th, 2024 9:00am - 3:00pm, PT
Seattle Children's Building Cure, McKinstry Auditorium, 1920 Terry Ave, Seattle, WA 98101
Agenda
Cassie Winter
T cells specific for mycobacterial lipids undergo antigen-independent activation and express anti-bacterial effector functions
Weihao Zheng PhD
A monocyte-derived lung cell subset that harbors M. tuberculosis is hyporesoponsive to IFNɣ
Virginia Pichler
Unveiling the diversity of clinical Mycobacterium abscessus infections: morphological spectrum, glycopeptidolipids and infection dynamics in macrophages.
Kim Foster
CD4 T cell-induced IDO-1 in non-hematopoietic cells shapes granuloma formation in the setting of pre-existing immunity to Mycobacterium tuberculosis
Nafsika Panagiotopoulou
Opening a backdoor to the tuberculosis granuloma by vaccine-promoted High Endothelial Venules
Talia Himmelfarb MD
Maternal mycobacterial-specific T-cell signatures and infant immune outcomes
Yichu Liang
Inhibition of PPM1A for host-directed tuberculosis therapy
Christine Qabar
Leveraging a synthetic biology approach to enhance BCG-mediated expansion of Vɣ9Vδ2 T-cells
Molly Kanagy
CXCR2 Inhibition limits Neutrophil-Driven Tissue Destruction and Decreases Bacterial Burdens
Marian Fairgrieve
Factors determining the failure of innate immunity to control M. tuberculosis
Allison Tammen
Two-pore channel endosomal calcium signaling enables MR1 presentation of Mycobacterium tuberculosis
Isabel Lamb-Echegaray
Elucidating the mechanism and correlates of protection elicited by CDN adjuvanted vaccines for M. tuberculosis.
Antonio Pagán PhD
“Non-canonical” roles of autophagy-related proteins in anti-mycobacterial immunity
Vishant Boradia PhD
Unraveling the role of PE/PPE proteins in tuberculosis drug resistance
Mario Arrieta-Ortiz PhD
Monocyte transcriptome remodeling sheds light into molecular signatures of pulmonary tuberculosis
Registration
Suggested lodging
Even Hotel, 527 Fairview Ave N, Seattle 98109
History
PacTB was first hosted by the Center for Emerging and Neglected Diseases at UC Berkeley in 2017.