presented by
![placeholder](/sites/default/files/inline-images/placeholder.png)
TRTC
UW Tuberculosis Research and Training Center
![SEATRAC logo](/sites/default/files/inline-images/SEATRAC%20circle%20square_0.jpg)
SEATRAC
Fred Hutch, University of Washington, Seattle Children's
Sponsored in part by
![Seattle Children's Research Institute](/sites/default/files/inline-images/OIP_1.jpg)
Seattle Children's
Research Institute
Overview
Focusing on basic science, the 2024 Pacific Tuberculosis Pathogenesis and Host-Response Research Retreat (PacTB) will feature early-stage investigator talks and posters.
May 6th, 1:00pm - 6:00pm, PT
May 7th, 2024 9:00am - 3:00pm, PT
Seattle Children's Building Cure, McKinstry Auditorium, 1920 Terry Ave, Seattle, WA 98101
Agenda
![Cassie Winter](/sites/default/files/inline-images/Winter%2C%20Cassie_Headshot%20.jpg)
Cassie Winter
T cells specific for mycobacterial lipids undergo antigen-independent activation and express anti-bacterial effector functions
![placeholder](/sites/default/files/inline-images/Weihao%20Zheng.png)
Weihao Zheng PhD
A monocyte-derived lung cell subset that harbors M. tuberculosis is hyporesoponsive to IFNɣ
![placeholder](/sites/default/files/inline-images/person%20name%20tag.png)
Virginia Pichler
Unveiling the diversity of clinical Mycobacterium abscessus infections: morphological spectrum, glycopeptidolipids and infection dynamics in macrophages.
![placeholder](/sites/default/files/inline-images/2024%20Kim%20Headshot.jpg)
Kim Foster
CD4 T cell-induced IDO-1 in non-hematopoietic cells shapes granuloma formation in the setting of pre-existing immunity to Mycobacterium tuberculosis
![placeholder](/sites/default/files/inline-images/NafsikaPanagiotopoulou.jpg)
Nafsika Panagiotopoulou
Opening a backdoor to the tuberculosis granuloma by vaccine-promoted High Endothelial Venules
![placeholder](/sites/default/files/inline-images/Himmelfarb%2C%20Talia_1.jpg)
Talia Himmelfarb MD
Maternal mycobacterial-specific T-cell signatures and infant immune outcomes
![placeholder](/sites/default/files/inline-images/YL_photo.jpg)
Yichu Liang
Inhibition of PPM1A for host-directed tuberculosis therapy
![placeholder](/sites/default/files/inline-images/person%20name%20tag_0.png)
Christine Qabar
Leveraging a synthetic biology approach to enhance BCG-mediated expansion of Vɣ9Vδ2 T-cells
![placeholder](/sites/default/files/inline-images/person%20name%20tag_1.png)
Molly Kanagy
CXCR2 Inhibition limits Neutrophil-Driven Tissue Destruction and Decreases Bacterial Burdens
![placeholder](/sites/default/files/inline-images/person%20name%20tag_2.png)
Marian Fairgrieve
Factors determining the failure of innate immunity to control M. tuberculosis
![placeholder](/sites/default/files/inline-images/Tammen%2C%20Allison.jpg)
Allison Tammen
Two-pore channel endosomal calcium signaling enables MR1 presentation of Mycobacterium tuberculosis
![placeholder](/sites/default/files/inline-images/Isabel%20D.%20Lamb-Echegaray%20%286%29.jpg)
Isabel Lamb-Echegaray
Elucidating the mechanism and correlates of protection elicited by CDN adjuvanted vaccines for M. tuberculosis.
![placeholder](/sites/default/files/inline-images/Pagan%20AJ_photo.png)
Antonio Pagán PhD
“Non-canonical” roles of autophagy-related proteins in anti-mycobacterial immunity
![placeholder](/sites/default/files/inline-images/Vishant%20Boradia%20square_0.jpg)
Vishant Boradia PhD
Unraveling the role of PE/PPE proteins in tuberculosis drug resistance
![placeholder](/sites/default/files/inline-images/Mario_Arrieta-Ortiz_headshot.jpg)
Mario Arrieta-Ortiz PhD
Monocyte transcriptome remodeling sheds light into molecular signatures of pulmonary tuberculosis
Registration
Suggested lodging
Even Hotel, 527 Fairview Ave N, Seattle 98109
History
PacTB was first hosted by the Center for Emerging and Neglected Diseases at UC Berkeley in 2017.